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Table 4 Sensitivity and specificity of each screening instrument using a broadened definition of depression*

From: A study of the diagnostic accuracy of the PHQ-9 in primary care elderly

Instrument and Cutpoint Sensitivity (%) (95% CI) Specificity (%) (95% CI) + Likelihood Ratio - Likelihood Ratio
PHQ-9 Cutpoint     
≥6 77 69 2.5 0.34
  (56-90) (63-74)   
≥7 77 77 3.3 0.31
  (56-90) (70-81)   
≥8 77 83 4.4 0.28
  (57-89) (76-87)   
≥9 71 87 5.2 0.34
  (51-85) (80-91)   
≥10 59 89 5.1 0.47
  (40-74) (82-93)   
PHQ-2 Cutpoint     
≥1 82 67 2.5 0.26
  (62-94) (61-71)   
≥2 71 73 2.6 0.40
  (50-86) (66-78)   
≥3 53 90 5.5 0.52
  (35-67) (85-95)   
≥4 35 98 18.4 0.66
  (21-40) (94-100)   
≥5 18 98 9.2 0.84
  (7-22) (95-100)   
15-item GDS Cutpoint     
≥4 94 4 0.98 1.63
  (85-99) (1-5)   
≥5 88 14 1.0 0.93
  (71-96) (8-16)   
≥6 81 62 2.1 0.30
  (60-93) (55-65)   
≥7 56 79 2.7 0.55
  (36-74) (73-84)   
≥8 31 90 3.3 0.76
  (16-46) (86-95)   
  1. * Bolded cutpoints indicate the optimum balance between sensitivity and specificity.
  2. CI = confidence interval.