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Table 3 Odds of having chest wall syndrome (CWS) for all potential predictors and availability of each variable for external validation. Final variables retained for the clinical prediction rule are given in bold

From: Development and validation of a clinical prediction rule for chest wall syndrome in primary care

Simple variables

OR CWS vs. others (95% CI)

P-value

Available forexternal validation

Trivial (history and physical examination)

9.11 (5.52-15.03)

<0.001

No

Pain reproducible by palpation

6.47 (4.58-9.15)

<0.001

Yes

No history of coronary heart disease

5.12 (2.88-9.12)

<0.001

Yes

Pain not retrosternal

5.08 (2.94-8.78)

<0.001

Yes

Absence of general practitioner’s concern

4.96 (2.79-8.84)

<0.001

Yes

Pain well localized (history)

2.65 (1.91-3.67)

<0.001

Yes

Pain superficial

2.48 (1.72-3.56)

<0.001

No

Pain well localized (physical examination)

2.46 (1.78-3.39)

<0.001

Yes

Pain not oppressive

2.37 (1.69-3.31)

<0.001

Yes

Pain related to position

2.13 (1.48-3.06)

<0.001

No

Stabbing pain

2.11 (1.38-3.24)

0.001

Yes

Pain related to movement

2.06 (1.42-3.01)

<0.001

Yes

Pain is not burning

1.62 (0.94-2.77)

0.081

Yes

Pain is not spread

1.52 (1.03-2.25)

0.037

No

Pain is not deep

1.30 (0.95-1.78)

0.100

No

Pain related to breathing

1.19 (0.83-1.71)

0.344

Yes

Absence of stressful stimulus

1.15 (0.72-1.82)

0.560

No

Intermittent pain

0.95 (0.69-1.29)

0.723

Yes

Absence of patient’s concern

0.92 (0.67-1.26)

0.613

Yes

Radiating pain

0.78 (0.51-1.20)

0.255

Yes

Pain is accompanied by cough

0.83 (0.56-1.24)

0.361

Yes

Pain related to cough

0.57 (0.37-0.89)

0.013

No

Combined variables

   

Pain neither retrosternal nor oppressive

3.11 (2.24-4.33)

<0.001

Yes

Pain well localized (history and/or physical examination)

3.07 (2.17-4.35)

<0.001

Yes

Pain related to mechanical factors (position and/or movement)

2.56 (1.85-3.56)

<0.001

No

Pain is accompanied by digestive symptoms§

0.54 (0.35-0.85)

0.01

No

  1. §Gastroesophageal reflux and/or odynodysphagia and/or dysphagia and/or epigastralgia.
  2. Association of two simple variables.
  3. CWS chest wall syndrome, OR odd ratio.