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Table 2 Sensitivity, specificity, positive and negative predictive value of rubella vaccination history against rubella susceptibility

From: How useful is a history of rubella vaccination for determination of disease susceptibility? A cross-sectional study at a public funded health clinic in Malaysia

Rubella vaccination history

Rubella susceptibility

Total(%)

(anti-rubella IgG test)

Susceptible (IgG<10 IU/mL) N(%)

Immune (IgG≥10 IU/mL) N(%)

No history of vaccination or unknown vaccination status ( rubella susceptible)

31 (18.6%)

136 (81.4%)

167 (100%)

History of vaccination(rubella immuned)

26 (7.8%)

307 (92.2%)

333 (100%)

Total

57

443

500

  1. Sensitivity of rubella vaccination history for rubella susceptibility= 31/ (31+26 ) x 100 = 54.4% (95% CI: 40.7, 67.4%).
  2. Specificity of rubella vaccination history for rubella susceptibility= 307/ (307+136) x 100 = 69.3% (95% CI: 64.7, 73.5%).
  3. Positive predictive value of rubella vaccination history = 31/ (31+136) x 100 = 18.6% (95% CI: 13.1, 25.5%).
  4. Negative predictive value of rubella vaccination history = 307/ (307+26) x 100 = 92.2% (95% CI: 88.6, 94.7%).