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Table 5 Composite diagnostic characteristics of exercise test outcome (positive/non-conclusive tests)

From: Diagnostic characteristics and prognoses of primary-care patients referred for clinical exercise testing: a prospective observational study

Characteristic Exertional chest pain* and pathologic ST-T segment** Exertional chest pain and angina diagnosis according to patient’s opinion Exertional chest pain and pathologic ST-T segment and angina diagnosis according to patient’s opinion
(95% CI) (95% CI) (95% CI)
Number of patients with characteristic 26 74 15
Sensitivity 37.1% (26.8-48.9) 58.3% (49.6-66.5) 28.3% (18.0-41.6)
Specificity 92.5% (89.3-94.8) 78.5% (74.2-82.2) 96.6% (93.9-98.1)
Positive predictive value 59.9% (48.2-70.5) 45.0% (39.2-50.9) 71.5% (54.8-83.9)
Negative predictive value 83.0% (80.2-85.4) 86.2% (83.4-88.5) 81.7% (79.0-84.1)
Likelihood ratio for positive test 4.9 (3.1-7.9) 2.7 (2.1-3.4) 8.3 (4.0-18.0)
Likelihood ratio for negative test 0.7 (0.6-0.8) 0.5 (0.4-0.7) 0.7 (0.6-0.9)
Pre-test probability of having a positive/non-conclusive exercise test 23.2% 23.2% 23.2%
Net gain after positive result 36.7% (25.0-47.3) 21.8% (16.0-27.7) 48.3% (31.6-60.7)
Number of patients with characteristic per positive/non-conclusive exercise test 1.7 2.2 1.4
  1. *Chest pain when walking uphill or in a hurry. **Pathologic ST-T segment on resting electrocardiogram. Patient’s opinion of angina diagnosis: yes or no. CI: confidence interval. Positive exercise test: angina symptoms and ST-segment depression >0.1 mV during the test. Non-conclusive test: angina or ST depression. Negative test: neither angina nor ST depression.