Primary endpoints | Secondary endpoints |
---|---|
1. The number of newly detected patients with a CMD in one year follow-up | 1. Difference in primary outcome 5 after implementation of different response-enhancing strategies |
2. Change in individual risk factors (smoking, physical inactivity, obesity, unhealthy diet, blood pressure and cholesterol levels) for CMD between baseline and one year follow-up | 2. Change in willingness to change lifestyle between baseline and one year follow-up |
3. The expected number of newly detected patients with CMD and mortality after 5, 10,20 years and lifetime | 3. Change in health status between baseline and one year follow up |
4. Costs-effectiveness of PPA CMR | |
5. Non-participation and compliance in different stages of PPA CMR |