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Table 2 Patient factors associated with willingness to switch to oral therapy on initial questionnaire.

From: Oral vitamin B12therapy in the primary care setting: a qualitative and quantitative study of patient perspectives

  No. (%) of subjects Unadjusted Adjusted*
Patient factor Willing to switch n = 63 Not willing to switch n = 23 OR (95% CI) p-value OR (95% CI) p-value
Time to clinic
0–29 minutes 49 (87) 7 (13) 9.34 <0.001 9.29 0.003
30+ minutes 12 (43) 16 (57) (3.14–27.78)   (2.16–39.97)  
Perceived disadvantages of injections
   Frequent visits to see MD/nurse
   Agree 38 (86) 6 (14) 4.31 0.010 5.41 0.038
   Disagree 25 (60) 17 (40) (1.49–12.42)   (1.10–26.56)  
   Cost to health care system
   Agree 26 (93) 2 (7) 7.38 0.010 16.68 0.023
   Disagree 37 (64) 21 (36) (1.59–34.23)   (1.51–184.22)  
  1. * Adjusted for patient factors at least weakly associated (i.e., p < 0.20) with a willingness to switch to oral B12 therapy in bivariate analyses: gender, time to clinic, satisfaction with past B12 injections, perceived disadvantages of injections (shots are painful, frequent visits to see MD/nurse, cost to health care system), perceived disadvantage of pills (won't see MD/nurse as often)