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Table 1 Demographic and clinical characteristics, and drug treatment of patients with preserved and with impaired left ventricular systolic function.

From: Natriuretic peptide vs. clinical information for diagnosis of left ventricular systolic dysfunction in primary care

Variables

Patients with preserved systolic function (n = 519)

Patients with impaired systolic function (n = 23)

P*

Patient characteristics

   

   Age, years,

63 (62 to 63)

69 (66 to 73)

0.003

   Male, %

57

70

0.241

   BMI

29 (29 to 30)

29 (27 to 31)

0.854

   Systolic BP, mm Hg

151 (149 to 152)

146 (138 to 155)

0.342

   Diastolic BP, mm Hg

86 (85 to 86)

83 (78 to 89)

0.361

   Ejection Fraction, %

61 (60 to 62)

41 (38 to 45)

<0.001

   NT-proBNP, pg/ml

218 (174 to 259)

1154 (236 to 2072)

<0.001

Symptoms

   

   Dyspnea at exertion, %

34

74

<0.001

   Dyspnea at rest, %

1

9

0.003

   Ankle swelling, %

33

74

<0.001

Medical history

   

   Diabetes, %

31

39

0.400

   Hypertension, %

86

96

0.184

   Hyperlipidemia, %

51

74

0.032

   CAD, %

29

65

<0.001

   Myocardial infarction, %

7

22

0.019

   Fam. history heart disease, %

42

57

0.168

Drug treatment

   

   Diuretics, %

42

74

0.003

   β blockers, %

57

74

0.105

   Calcium channel blockers, %

23

22

0.928

   ACE inhibitors, %

46

52

0.564

   AT1 blockers, %

16

26

0.201

   Lipid lowerings agents, %

35

74

<0.001

  1. * T-Test or χ2-Test.
  2. values in mean (95% confidence interval) unless otherwise indicated.
  3. BMI Body Mass Index; BP blood pressure; CAD coronary artery disease; ACE angiotension converting enzyme, AT1 blocker angiotensin II type 1 receptor blocker.