From: Interventions to improve adherence to cardiovascular disease guidelines: a systematic review
Education compared to control for improving adherence to cardiovascular disease guidelines | ||||||
---|---|---|---|---|---|---|
Patient or population: patients with improving adherence to cardiovascular disease guidelines | ||||||
Settings: | ||||||
Intervention: Education | ||||||
Comparison: control | ||||||
Outcomes | Illustrative comparative risksa (95 % CI) | Relative effect | No of participants | Quality of the evidence | Comments | |
Assumed risk control | Corresponding risk Education | (95 % CI) | (studies) | (GRADE) | ||
Mortality | Study population | OR 0.54 | 2190 | ⊕ ⊕ ⊕⊝ | ||
Follow-up: median 6 months | 40 per 1000 | 22 per 1000 | (0.2 to 1.42) | (3 studies) | moderatec | |
(8 to 56) | ||||||
Moderate | ||||||
26 per 1000 | 14 per 1000 | |||||
(5 to 37)b | ||||||
Disease Targets | The mean disease targets in the intervention groups was0.32 standard deviations lower | 2145 | ⊕⊝⊝⊝ | SMD −0.32 (−0.71 to 0.07) | ||
Follow-up: 3–6 months | (6 studies) | very lowc,e,f | ||||
(0.71 lower to 0.07 higher) | ||||||
Adherence | The mean adherence in the intervention groups was 0.58 standard deviations higher | 322 | ⊕ ⊕ ⊕⊕ | SMD 0.58 (0.35 to 0.8) | ||
Follow-up: 6–24 months | (4 studies) | high | ||||
(0.35 to 0.8 higher) | ||||||
Mortality | Study population | OR 0.48 | 355 | ⊕ ⊕ ⊝⊝ | ||
Follow-up: 7 months - 10 years | 182 per 1000 | 96 per 1000 | (0.11 to 1.98) | (4 studies) | lowg | |
(24 to 306) | ||||||
Moderate | ||||||
146 per 1000 | 76 per 1000 | |||||
(18 to 253)b | ||||||
Hospitalizations | Study population | OR 0.88 | 979 | ⊕ ⊕ ⊕⊕ | ||
Follow-up: 7–22 months | 188 per 1000 | 170 per 1000 | (0.54 to 1.41) | (4 studies) | high | |
(111 to 246) | ||||||
Moderate | ||||||
191 per 1000 | 172 per 1000 | |||||
(113 to 250)b | ||||||
Disease Targets | The mean disease targets in the intervention groups was 0.09 standard deviations lower | 2732 | ⊕ ⊕ ⊝⊝ | SMD −0.09 (−0.24 to 0.07) | ||
Follow-up: 7–27 months | (5 studies) | lowf,h | ||||
(0.24 lower to 0.07 higher) | ||||||
Adherence | Study population | OR 1.05 | 6019 | ⊕ ⊕ ⊝⊝ | ||
Follow-up: 7–27 months | 609 per 1000 | 620 per 1000 | (0.82 to 1.34) | (8 studies) | lowc,i | |
(561 to 676) | ||||||
Moderate | ||||||
236 per 1000 | 245 per 1000 | |||||
(202 to 293)b | ||||||
Adherence | Study population | OR 2.36 | 2145 | ⊕⊝⊝⊝ | ||
Follow-up: median 6 months | 288 per 1000 | 489 per 1000 | (0.86 to 6.51) | (5 studies) | very lowc,j,k | |
(258 to 725) | ||||||
Moderate | ||||||
326 per 1000 | 533 per 1000 | |||||
(294 to 759)b |