Intervention | Control | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
Clinical topic | N | Mean before (sd) | Mean after (sd) | n | Mean before (sd) | Mean after (sd) | Ba (95% CI) | icc | Direction | p |
Anaemia | ||||||||||
Iron preparations. oral | 35 | 29.5 (22.5) | 38.7 (25.6) | 53 | 26.6 (27.6) | 46.9 (54.2) | 18.9 (−3.9, 41.7) | 0.43 | = | 0.098 |
Urinary tract infections | ||||||||||
Antibiotics UTI | 8 | 40.8 (24.0) | 44.5 (29.7) | 80 | 46.5 (36.3) | 55.3 (44.8) | 6.3 (−21.1, 33.8) | 0.33 | ↓ | 0.623 |
Prostate complaints | 26 | 68.5 (47.0) | 79.5 (63.0) | 62 | 65.5 (53.6) | 125.9 (91.9) | 28.5 (6.5, 50.7) | 0.27 | ↓ | 0.016 |
Alpha receptor blockers | 26 | 57.5 (41.1) | 66.5 (54.2) | 62 | 54.0 (44.9) | 101.5 (73.2) | 44.2 (6.0, 82.3) | 0.49 | ↓ | 0.027 |
5 alpha reductase inhibitors | 26 | 11.0 (7.5) | 13.0 (11.7) | 62 | 11.5 (11.0) | 24.5 (22.9) | 11.1 (2.1, 20.2) | 0.05 | ↓ | 0.020 |
Stomach complaints | 28 | 455.1 (294.7) | 565.2 (303.7) | 60 | 275.7 (253.8) | 509.1 (433.0) | 61.1 (15.0, 107.2) | 0.11 | ↓ | 0.014 b |
H2 antagonists | 28 | 28.0 (22.4) | 32.4 (26.8) | 60 | 23.2 (22.35) | 24.2 (22.6) | −2.4 (−21.5, 16.7) | 0.68 | ↑ | 0.788 |
Proton pump inhibitors | 28 | 425.9 (276.1) | 531.5 (283.8) | 60 | 251.6 (234.0) | 483.7 (414.7) | 254.8 (60.1, 449.5) | 0.66 | ↓ | 0.014 b |
Misoprostol | 28 | 0 (0) | 0 (0) | 60 | 0.1 (0.4) | 0.1 (0.45) | 0.1 (−0.1, 0.2) | 0.01 | ↓ | 0.365 |
Triple therapy (ATC A02BD04) | 28 | 1.2 (2.5) | 1.4 (1.8) | 60 | 0.9 (1.2) | 1.1 (1.6) | 0.1 (−0.7, 0.8) | 0.20 | ↓ | 0.878b |
Thyroid dysfunction | 29 | 82.2 (45.9) | 99.2 (57.5) | 59 | 86.0 (63.1) | 128.5 (94.6) | 12.6 (0.7, 24.4) | 0.08 | = | 0.040 |
Thyroid hormones | 29 | 76.7 (43.5) | 91.1 (52.2) | 59 | 79.5 (58.8) | 118.3 (87.8) | 25.2 (2.1, 48.3) | 0.19 | = | 0.035 |
Antithyroid preparations | 29 | 5.5 (7.4) | 8.2 (13.2) | 59 | 6.5 (7.7) | 10.1 (14.0) | 0.2 (−4.2, 4.6) | 0.11 | ↑ | 0.927 |
Perimenopausal complaints | 24 | 59.4 (31.9) | 56.5 (25.9) | 64 | 51.2 (40.0) | 51.3 (40.0) | 1.5 (−2.3, 5.4) | 0.21 | ↓ | 0.414 |
Oestrogens. oral | 24 | 11.5 (8.0) | 9.7 (6.2) | 64 | 14.0 (14.0) | 12.3 (12.4) | 1.0 (−3.6, 5.5) | 0.03 | ↓ | 0.612 |
Contraceptives (>50y) | 24 | 5.1 (2.8) | 5.9 (2.7) | 64 | 3.2 (3.6) | 6.5 (5.1) | 2.5 (−0.9, 5.8) | 0.31 | ↓ | 0.137 |
Hormone replacement therapy | 24 | 38.7 (24.2) | 36.3 (21.0) | 64 | 31.1 (24.4) | 29.8 (24.4) | 2.6 (−9.7, 14.9) | 0.60 | ↓ | 0.652 |
Clonidine | 24 | 0.6 (1.5) | 0.7 (2.7) | 64 | 0.4 (1.5) | 0.4 (1.6) | −0.3 (−1.4, 0.7) | 0.11 | ↓ | 0.508 b |
Tibolon | 24 | 3.6 (3.7) | 3.8 (4.1) | 64 | 2.6 (3.0) | 2.3 (3.3) | −0.7 (−2.0, 0.6) | 0.00 | ↓ | 0.294 b |