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Table 3 Evidence summary [17] of cognitive tests for dementia (dementia versus no dementia)

From: How to choose the most appropriate cognitive test to evaluate cognitive complaints in primary care

Test

Studies (n)

Test time (min)

Cut-off score

Study population, % dementia

Number of participants analysed

Sens (95% CI)

Spec (95% CI)

PPV (95% CI)

NPV (95% CI)

AMT

2

 

7/8

29

269

42 (31, 53)

93 (89, 96)

71 (56, 83)

80 (74, 85)

  

7/8

4

358

92 (64, 100)

95 (93, 97)

43 (25, 63)

100 (98, 100)

Mini-Cog

2

3–4

2/3

40

371

97 (93, 99)

71 (65, 77)

71 (64, 77)

97 (93, 99)

  

2/3

3

630

76 (54, 90)

73 (69, 76)

9 (5, 14)

99 (97,100)

MIS

3

4

4

10

483

80 (66, 90)

96 (94, 98)

70 (57, 82)

98 (96, 99)

  

4

18

318

76 (42, 100)

73 (56, 96)

38 (29, 47)

94 (89, 97)

  

4

12

240

86 (67, 96)

97 (94, 99)

80 (61, 92)

98 (95, 100)

MMSE

5

7–10

23/24

4

1115

91 (78, 98)

87 (85, 89)

23 (17, 29)

100 (99, 100)

  

23/24

1

709

87 (78, 95)

89 (86, 92)

52 (44, 60)

98 (96, 99)

  

23/24

4

358

77 (46, 95)

97 (94,98)

46 (24, 68)

99 (97, 100)

  

23/24

6

648

88 (74, 96)

88 (85, 90)

32 (24, 42)

99 (98, 100)

  

23/24

28

360

84 (75, 90)

88 (84, 92)

73 (64, 81)

94 (90, 96)

MMSE

4

7–10

24/25

29

283

81 (70, 88)

76 (70, 82)

57 (48, 67)

90 (85, 95)

  

24/25

4

269

98 (78, 100)

84 (79, 87)

21 (13, 33)

100 (99, 100)

  

24/25

14

274

85 (70, 94)

81 (75, 86)

42 (31, 54)

97 (94, 99)

  

24/25

19

449

84 (75, 91)

83 (79, 87)

55 (46, 63)

96 (93, 98)

MSQ

2

4

7/8

16

164

100 (87, 100)

84 (76, 89)

54 (39, 69)

100 (97, 100)

  

7/8

4

358

92 (64, 100)

98 (96, 99)

67 (41, 87)

100 (98, 100)

SPMSQ

2

3–4

7/8

3

119

100 (29, 100)

100 (97, 100)

100 (29, 100)

100 (97, 100)

   

7/8

4

358

100 (75, 100)

97 (94, 98)

54 (33, 75)

100 (99, 100)

  1. Only the studies reporting a cut-off score that was studied more than once are depicted in the table. Abbreviations: CI Confidence Interval, MCI Mild Cognitive Impairment, NR Not Reported; Sens Sensitivity, Spec Specificity, NPV Negative Predictive Value, PPV Positive Predictive Value, AUC Area Under the Curve. Abbreviations cognitive tests: AMT Abbreviated Mental Test, MIS Memory Impairment Screen, MMSE Mini Mental State Examination, MSQ Mental Status Questionnaire, SPMSQ Short Portable Mental Status Questionnaire