Pharmacotherapy | Urban area (n = 56)a | Rural area (n = 75)a | Island area (n = 66)a | P b |
---|---|---|---|---|
First-line treatment (n, (%)) | ||||
1. Diuretics | 3 (5.4) | 8 (10.7) | 1 (1.5) | 0.037 |
2. ACE inhibitors (ACEI) | 14 (25.0) | 21 (28.0) | 15 (22.7) | |
3. Calcium channel blockers (CCB) | 16 (28.6) | 5 (6.7) | 9 (13.6) | |
4. Angiotensin II receptor blockers (ARB) | 0 (0.0) | 0 (0.0) | 1 (1.5) | |
5. β-adrenergic receptor blockers (BB) | 5 (8.9) | 8 (10.7) | 14 (21.2) | |
7. Fixed-dose combination:c | 8 (14.3) | 12 (16.0) | 7 (10.6) | |
ACEI + diuretic | 5 (8.9) | 9 (12.0) | 5 (7.6) | |
BB + diuretic | 2 (3.6) | 0 (0.0) | 2 (3.0) | |
ARB + diuretic | 0 (0) | 1 (1.3) | 0 (0.0) | |
ACEI + CCB | 1 (1.8) | 2 (2.7) | 0 (0.0) | |
8. > 1 medications (2 or 3)c | 10 (17.9) | 21 (28.0) | 19 (28.8) | |
One-year treatment (median, 95% CI) | ||||
Total daily number of pills per patientd | 1.5 (1.0–2.0) | 1.5 (1.0–2.0) | 2 (1.0–2.6) | 0.217 |
Total annual number of drugs per patient | 1 (1.0–2.0) | 2 (1.0–2.0) | 1 (1.0–2.0) | 0.135e |