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Table 3 Univariate and multivariate regression of VAS with medical, social and psychological factors (GPs’ perspective)

From: Factors associated with patients’ and GPs’ assessment of the burden of treatment in multimorbid patients: a cross-sectional study in primary care

Description

Value

Unvariable regressions

Multivariable regression

Beta coefficient (95% CI)

p-value

Beta coefficient (95% CI)

p-value

VIF*

Patient’s age in years

 

−0.014 (− 0.023;-0.005)

0.002

−0.015 (− 0.023;-0.007)

< 0.001

1.185

Patient’s gender

 

−0.213 (− 0.428;0.002)

0.052

   

Location of practice (ref: Urban)

Semi-urban/suburban

0.000 (−0.417;0.417)

1.000

   

Rural

0.065 (−0.491;0.620)

0.820

   

Marital status (ref: Single)

Married

−0.226 (− 0.602;0.149)

0.237

   

Separated/divorced

0.110 (−0.318;0.538)

0.614

   

Widow

−0.211 (− 0.614;0.193)

0.306

   

Highest level of schooling achieved (ref: Compulsory education)

Upper secondary level

−0.116 (− 0.402;0.171)

0.428

   

Tertiary level

−0.123 (− 0.408;0.162)

0.398

   

GP assessment of number of chronic conditions

 

0.165 (0.124;0.206)

< 0.001

0.069 (0.031;0.107)

< 0.001

1.239

CIRCS

 

1.765 (1.488;2.042)

< 0.001

1.267 (1.015;1.520)

< 0.001

1.088

Total number of different pharmacological treatment the patient is currently taking

 

0.196 (0.165;0.227)

< 0.001

0.102 (0.070;0.134)

< 0.001

1.380

Use of a pillbox (dispenser)

 

0.595 (0.383;0.807)

< 0.001

0.136 (−0.045;0.317)

0.142

1.106

Home-based care (patient report)

 

0.964 (0.623;1.305)

< 0.001

0.336 (0.041;0.631)

0.026

1.133

Total EQ-5D-3 L score

 

−0.036 (−0.042;-0.031)

< 0.001

−0.016 (− 0.022;-0.010)

< 0.001

1.681

EQ-5D-3 L health scale (VAS, 0–100)

 

−0.026 (− 0.031;-0.020)

< 0.001

−0.005 (− 0.010;0.000)

0.056

1.393

Deprivation score (DipCare)

 

0.496 (0.385;0.607)

< 0.001

   

Health literacy score (HLS EU 6)

 

−0.612 (−0.855;-0.369)

< 0.001

− 0.176 (− 0.382;0.030)

0.093

1.133

Hypertension

 

−0.150 (− 0.396;0.096)

0.231

   

Cardiovascular risk

 

−0.225 (− 0.453;0.002)

0.052

   

Diabetes

 

−0.047 (− 0.279;0.185)

0.691

   

Obesity

 

−0.027 (− 0.261;0.207)

0.823

   

Ischemic heart disease

 

0.156 (−0.079;0.392)

0.193

   

Depression

 

0.673 (0.429;0.916)

< 0.001

   

Knee osteoarthritis

 

0.192 (−0.060;0.445)

0.136

   

General pain

 

0.794 (0.534;1.055)

< 0.001

0.198 (−0.029;0.425)

0.087

1.135

Atrial fibrillation

 

0.287 (0.024;0.549)

0.032

0.233 (0.009;0.457)

0.042

1.135

  1. * variance inflation factor to exclude co-linearity